‏ Ephesians 4:18

 Being darkened ( εσκοτωμενο οντες ). Periphrastic perfect passive participle of  σκοτοω, old verb from  σκοτος (darkness), in N.T. only here and Re 9:2; 16:10.

 In their understanding ( τη διανοια ). Locative case. Probably  διανοια ( δια, νους ) includes the emotions as well as the intellect ( νους ). It is possible to take  οντες with  απηλλοτριωμενο (see 2:12) which would then be periphrastic (instead of  εσκοτωμενο ) perfect passive participle.

 From the life of God ( της ζωης του θεου ). Ablative case  ζωης after  απηλλοτριωμενο (2:12).

 Because of the ignorance ( δια την αγνοιαν ). Old word from  αγνοεω, not to know. Rare in N.T. See Ac 3:17.

 Hardening ( πωρωσιν ). Late medical term (Hippocrates) for callous hardening. Only other N.T. examples are Mr 3:5; Ro 11:25.

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